HLA typing in immune thrombocytopenic purpura
نویسندگان
چکیده
منابع مشابه
Acute Immune Thrombocytopenic Purpura in Infants
Abstract Objective Immune thrombocytopenic purpura (ITP) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. The characteristics of acute ITP in infants have rarely been described. In order to better understand acute ITP in infants, the characteristics of the disease at this age group was investigated. Material and Methods The present des...
متن کاملViral-associated immune thrombocytopenic purpura.
Chronic immune thrombocytopenic purpura (CITP) is a diagnosis of exclusion that occurs either de novo or secondary to other underlying disorders. Chronic infection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are now well-characterized causes of CITP. Between 6% and 15% of patients infected with HIV may develop thrombocytopenia. Patients with CITP with risk factors for HI...
متن کاملImmune thrombocytopenic purpura of childhood.
Immune mediated thrombocytopenia (ITP) is a common manifestation of autoimmune disease in children. Although patients often present with bruises, petechiae, and some mucosal bleeding, the incidence of life-threatening hemorrhage is rare (0.2-0.9%) but can be fatal when presenting in vital organs. A wide range of therapeutic regimens are currently in use, including observation alone, as the majo...
متن کاملGenetic analysis of HLA-typing in Chinese patients with idiopathic thrombocytopenic purpura.
Adult chronic idiopathic thrombocytopenic purpura (ITP) is a common hematologic disease worldwide. The pathogenesis involves formation of auto-antibodies against platelet glycoproteins. The mechanism of autoimmunity is not fully understood but may involve binding of antigenic peptides to HLA antigens.1 Therefore, specific HLA alleles may be associated with the occurrence of ITP. However, this a...
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1. Jadavji T, Scheifele D, Halperin S; Canadian Paediatric Society/Health Cananda Immunization Monitoring Program. Thrombocytopenia after immunization of Canadian children, 1992 to 2001. Pediatr Infect Dis J. 2003;22:119-22. 2. Arya LS, Ghai OP, Saraya AK. Thrombocytopenic purpura following DPT vaccination. Pediatr Hematol Oncol. 1993;10:381-3. 3. Hsieh YL, Lin LH. Thrombocytopenic purpura foll...
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ژورنال
عنوان ژورنال: Major Histocompatibility Complex
سال: 1995
ISSN: 2186-9995,2187-4239
DOI: 10.12667/mhc.2.16